Rutgers Main | CIRC | Quantitative Biology   
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Qing Dai

An active site rearrangement within the Tetrahymena group I ribozyme releases nonproductive interactions and allows formation of catalytic interactions.

RNA, (2016) 22, 32-48
DOI: 10.1261/rna.053710.115 Download PDF

Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2'-O-transphosphorylation

Proc. Natl. Acad. Sci. USA, (2013) 110, 13002-13007
DOI: 10.1073/pnas.1215086110 Download PDF